Neuron Specific Enolase, Recombinant, His-Tag, aa1-434 (NSE)
Description
Purity ~95% (SDS-PAGE 12%). NSE is the gamma/gamma isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival. Source: Recombinant protein corresponding to aa1-434 of NSE, fused to 6His-tag expressed in E. coli. Applications: Suitable for use in ELISA.