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Description
Purified anti-ch-TOG. ch-TOG (also known as colonic and hepatic tumor over-expressed protein) is a 218 kD member of the TOG/XMAP215 family containing heat repeats. This protein is localized in the perinuclear cytoplasm during interphase and at the spindle poles and centrosomes during mitosis. Ch-TOG is believed to function in spindle microtubule organization and has been shown to interact with TACC1, TACC3,and tubulin. The Poly6204 antibody has be shown to be useful for Western blotting of the human ch-TOG protein.
Immunogen
Partial recombinant protein, containing approximately 200 amino acids from the C-terminus