An inhibitor of microtubule assembly (ID50 = 2 μM) with anticancer properties; inhibits proliferation of hepatocellular carcinoma (IC50s = 9.2-728.2 nM) and other carcinoma cell lines (IC50s = 12.2-2,247 nM); inhibits tumor growth in a hepatocellular carcinoma mouse xenograft model when administered at doses of 2 or 4 mg/kg for 4 weeks; decreases functional vascular volume within hours in a well-vascularized murine colon adenocarcinoma model