Purity ~85% (SDS-PAGE). Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, Pin4 protein binds to double-stranded DNA under physiological salt conditions. Source: Recombinant protein corresponding to aa1-156 from human PIN4, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~18.8kD (176aa, aa1-156 + NT His Tag) Specific Activity: >300nmoles/min/mg, defined as the amount of enzyme that cleaves 1umole of Suc-AAFP-pNA.minute at 25°C in Tris HCl pH 8.0 using chymotrypsin. AA Sequence: MGSSHHHHHH SSGLVPRGSH MPMAGLLKGL VRQLERFSVQ QQASKMPPKG KSGSGKAGKG GAASGSDSAD KKAQGPKGGG NAVKVRHILC EKHGKIMEAM EKLKSGMRFN EVAAQYSEDK ARQGGDLGWM TRGSMVGPFQ EAAFALPVSG MDKPVFTDPP VKTKFGYHII MVEGRK