MW: 23.4kDa (215aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. NuDT16 is nuclear nucleoside diphosphatase proteins localized within foci in the nucleolus and nucleoplasm. This is a RNA-decapping enzyme that binds specifically to u8 snoRNA. It can remove m7G and m227G caps from RNAs, rendering them substrates for 5'-3' exonucleases for degradation in vivo. Recombinant human NuDT16 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatogr