產(chǎn)品名稱 PRT4165 from LIFESPAN BIOSCIENCES INC.
    產(chǎn)品貨號 LS-H3766
    產(chǎn)品價格 現(xiàn)貨詢價，電話：010-67529703
    產(chǎn)品規(guī)格 n/a
    產(chǎn)品品牌 LIFESPAN BIOSCIENCES INC.
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NamePRT4165
    DescriptionPurity >98% by HPLC. PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1, RNF2, and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX. In addition, it prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2a (Top2a).
    Sizen/a
    Concentrationn/a
    Applicationsn/a
    Other Names2-(3-Pyridinylmethylene)-1H-Indene-1,3(2H)-dione, NSC600157
    Gene, Accession, CAS #CAS: 31083-55-3
    Catalog #LS-H3766
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    Order / More InfoPRT4165 from LIFESPAN BIOSCIENCES INC.
    Product Specific Referencesn/a
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