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Description
Purified anti-FMIP. FMIP, also known as FMS-Interacting Protein and THOC5, is a member of the THO complex, which is part of the larger TREX (transcription/export) complex. The TREX complex binds specifically to spliced mRNA, where it binds upstream of the exon-junction complex and aids in mRNA export. TREX machinery is also utilized by Kaposi’s sarcoma-associated herpesvirus and certain other viruses for the propagation of virus production. FMIP may also be involved in granulocyte and adipocyte differentiation.
Immunogen
This monoclonal antibody was raised against a bacterially expressed C-terminal recombinant GST fusion protein derived from 3' 2.25 kb EcoRV-EcoR1 FMIP cDNA fragment.
Other Names
THOC5, C22orf19, PK1.3, fSAP79, hTREX90, THO complex subunit 5 homolog, PP39.2, hTREX90, placental protein 39.2, Fms-interacting protein, NF2/meningioma region protein pK1.3, functional spliceosome-associated protein 79, MMS-5281-100