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Description
VPREB1/CD179a Polyclonal Antibody. ? Target Background: VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are
Immunogen
KLH conjugated synthetic peptide derived from human VPREB1/CD179a
Other Names
CD179 antigen like family member A; CD179 antigen-like family member A; CD179a; IGI; IGVPB; Immunoglobulin iota chain; Pre B lymphocyte 1; pre-B lymphocyte 1; Protein VPreB1; VpreB protein; VPREB 1; VPREB; VpreB protein; VPREB_HUMAN; VPREB1.