MW: 68,780 Da. Purity >85% (SDS-PAGE). This protein shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3
Size
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Concentration
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Applications
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Other Names
[cell division cycle protein 23 homolog; Cell division cycle protein 23 homolog; cell division cycle protein 23 homolog; cell division cycle 23; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8]