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Description
PE/Cy7 anti-mouse lymphotoxin beta receptor (LTβR). LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KD receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.
Immunogen
E.coli expressed extracellular domain of mouse lymphotoxin beta receptor
Other Names
LTbR, TNFRIII, TNF receptor-related protein (TNFRrp)