Recombinant Escherichia coli DNA helicase II (uvrD)
Description
Purity > 85% as determined by SDS-PAGE. MW: 82kDa. Full Length: 1-720aa. tag-Free. Escherichia coli (strain K12). A helicase with DNA-dependent ATPase activity. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand. Initiates unwinding more efficiently from a nicked substrate than ds duplex DNA. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair, and probably also in repair of alkylated DNA