Recombinant Escherichia coli DNA mismatch repair protein MutL (mutL)
Description
Purity > 90% as determined by SDS-PAGE. MW: 71.9kDa. Full Length: 1-615aa. N-terminal 6xHis-tagged. Escherichia coli (strain K12). This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker, a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA.