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Description
Mouse Anti-ARHGEF18 Recombinant Antibody (GT1972). Provided herein is a Mouse monoclonal antibody against Human Rho/Rac Guanine Nucleotide Exchange Factor 18. The antibody can be used for immunoassay techniques, such as WB. Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain.