產(chǎn)品名稱 ARHGEF18 Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號 MA5-27295
    產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
    產(chǎn)品規(guī)格 100 μl
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificityARHGEF18
    CloneOTI6D10
    Host SpeciesMouse
    Reactive Specieshuman
    IsotypeIgG1
    Formatpurified
    Size100 μl
    Concentrationn/a
    ApplicationsImmunohistochemistry (Paraffin): 1:500, Western Blot: 1:500-1:2000
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionARHGEF18 Monoclonal Antibody (OTI6D10). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. Its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production. Required for EPB41L4B-mediated regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950).
    Immunogenn/a
    Other NamesP114-RhoGEF, 114 kDa Rho-specific guanine nucleotide exchange factor, P114-RHO-GEF, Rho-specific guanine nucleotide exchange factor p114, Rho/Rac guanine nucleotide exchange factor 18, SA-RhoGEF, p114RhoGEF, rho guanine nucleotide exchange factor 18, septin-associated RhoGEF
    Gene, Accession #Entrez: 23370; Uniprot: Q6ZSZ5
    Catalog #MA5-27295
    Price
    Order / More InfoARHGEF18 Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
    產(chǎn)品資料

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