Recombinant Human Integrin alpha-V (ITGAV), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 19.7kDa. Partial: 891-1048aa. N-terminal 6xHis-tagged. Homo sapiens (Human). The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with Extracellular domain viral Tat protein ses to enhance angiogenesis in Kaposi's sarcoma lesions.