Recombinant Human Interleukin-21 protein (IL21) (Active)
Description
Purity > 97% as determined by SDS-PAGE and HPLC. MW: 15.4kDa. Full Length of Mature Protein: 23-155aa. tag-Free. Homo sapiens (Human). Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. {ECO:0000250, ECO:0000269|PubMed:11081504, ECO:0000269|PubMed:15178704}.