Purified (~70-90%). EEF2K is a highly conserved calmodulin-dependent protein kinase that links activation of cell surface receptors to cell division. EEF2K is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2), an abundant cytoplasmic protein that catalyzes the movement of the ribosome along mRNA during translation in eukaryotic cells, and inhibits the EEF2 function. EEF2K is highly expressed in heart and skeletal muscle, suggesting that EEF2 phosphorylation may be particularly important in muscle. EEF2K is highly expressed in patients with systemic lupus erythematosus as well as in many cancers. Source: Recombinant protein corresponding to human EEF2K, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~125kD Specific Activity: 50nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL)