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Description
The scaffolding protein is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression.The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Synonyms: Polyclonal CAV1 antibody, Anti-CAV1 antibody, caveolin 1, caveolae protein, 22kDa antibody, CAV antibody, MSTP085 antibody, VIP21 antibody.
Immunogen
CAV1 antibody was raised in rabbit using the N terminal of CAV1 as the immunogen