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Description
Function: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.Subcellular location: Golgi apparatus membrane, Single-pass membrane protein. Cell membrane, Single-pass membrane protein. Note: Potential hairpin-like structure in the membrane. Membrane protein of protein of caveolae.Tissue specificity: In muscle and lung, less so in liver, brain and kidney. Also known as: CAV1, CAV.
Immunogen
A synthetic peptide from the 1t cytoplasmic domain of human Caveolin-1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many other species including rat, mouse.