A natural sesterterpenoid which irreversibly inhibits sPLA2 isoforms from human synovium, bee venom, and cobra venom (IC50 values are 3.9, 7.5, and 2 μM, respectively); also potently blocks calcium channels (IC50 = 1 μM) and inhibits PLC (IC50 = 1.5 μM)
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
naturals products inhibitors inhibits inhibitions phospholipases channels blockers inflammation cancers sesterterpenoid secretory phospholipase A2 sPLA2 isoforms human synovium bees venom cobras phospholipase C biochemical cellular in vivo experiments PLCs calcium channels