Recombinant Human 5-formyltetrahydrofolate cyclo-ligase (MTHFS)
Description
Purity > 90% as determined by SDS-PAGE. MW: 39.1kDa. Full Length of Mature Protein: 2-203aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.