Purity: > 90% by SDS - PAGE Format: Liquid in 50mM Tris pH 8.0, 0.1mM PMSF, 1mM EDTA, 1mM DTT, 10% glycerol. . Protein phosphatase inhibitor-1(IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Protein phosphatase inhibitor-1, Protein phosphatase inhibitor, Protein phosphatase inhibitor-1 Protein phosphatase inhibitor 1, I 1, I1, Inhibitor 1, IPP 1, IPP1, PPP1R1A, Protein phosphatase 1 regulatory (inhibitor) subunit 1A, Protein phosphatase 1 regulatory subunit 1A.