Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 40% glycerol, 200mM NaCl. LSM2 (u6 snRNA-associated Sm-like protein LSm2) belongs to the snRNP Sm proteins family. Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM2 binds specifically to the 3'-terminal u-tract of u6 snRNA. It is involved in pre-mRNA splicing. Recombinant human LSM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
u6 snRNA-associated Sm-like protein LSm2, G7b, snRNP