Purity: > 95% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT. MYCBP, also known as c-Myc binding protein, binds to the transactivation domain of c-Myc and stimulates the activation of E-box-dependent transcription. It translocates from the cytoplasm to the nucleus during S phase when increased expression of c-Myc occurs. It has also been shown to associate with AKAP 149 and AKAP 84 in mitochondria of somatic cells and sperm, which suggests a role for MYCBP in spermatogenesis. Recombinant human MYCBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.