Purity: > 80% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 0.2M NaCl, 2mM DTT. TCEAL7 plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. It associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. This protein regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres) and telomerase-positive cell lines. Recombinant human TCEAL7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Transcription elongation factor A (SII)-like 7, MPMGp800C04260Q003