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| Antigenic Specificity | ESAM |
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| Clone | 1G8/ESAM |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | TotalSeq?-A oligomer conjugate |
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| Size | 10 μg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq? reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq?-A0596 anti-mouse ESAM. Endothelial cell-selective adhesion molecule (ESAM) is a 55-kD membrane protein composed of two extracellular Ig domains, a single transmembrane domain, and a cytoplasmic domain. ESAM is predominantly expressed at endothelial junctions and on platelets, participating in the migration of neutrophils through the vessel wall by influencing endothelial cell contacts. It impacts vascular permeability and extravasation process. Recently, it was reported that ESAM is a novel marker for murine hematopoietic stem cells (HSCs) in fetal liver. ESAM expression is correlated with HSC activity. The ESAMHi population was highly enriched for multipotent myeloid-erythroid progenitors and primitive progenitors with lymphpoietic activity, and exclusively reconstituted long-term lymphohematopoiesis in lethally irradiated recipients. |
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| Immunogen | Mouse bEND.3 endothelial cells |
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| Other Names | Endothelial cell-selective adhesion molecule |
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| Gene, Accession # | Gene ID: 69524 |
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| Catalog # | 136209 |
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| Price | |
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| Order / More Info | ESAM Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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