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Description
Alexa Fluor? 594 anti-mouse CD185 (CXCR5). CD185 is also known as CXCR5. It is the receptor for chemokine CXCL13/BLC, which is chemotactic for B cells.? CXCR5 is expressed on B cells and a subset of T cells in the spleen, neuronal tissue, lymph nodes, and bone marrow.? It is important for migration of B cells into the B cell follicles of the spleen and Peyer’s patches.? Follicular helper T cells (Tfh) also express CXCR5 and the ability of these cells to migrate to the lymph node is modulated by the balanced expression of CCR7 and CXCR5.