2-113aa, Full Length of Mature Protein. MW: 12,707 Da. Purity >85% (SDS-PAGE). This protein is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullinCDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the
[RING-box protein 2 isoform 2; RING-box protein 2; RING-box protein 2; ring finger protein 7; RING finger protein 7; Sensitive to apoptosis gene protein]