CREB Binding Protein bromodomain (1081-1197 aa) (GST-tagged), Human recombinant
Description
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. The cAMP response element-binding protein (CREB) binding protein (CREBBP) bromodomain has been shown to modulate the stability and function of
Size
20 μg
Concentration
n/a
Applications
RUO
Other Names
cAMP-responsive element-binding protein 1 CREB-1; CBP; CREBBP