Recombinant Human Galectin-3 protein (LGALS3) (Active)
Description
Purity > 98% as determined by SDS-PAGE and HPLC. MW: 26.0kDa. Full Length of Mature Protein: 2-250aa. tag-Free. Homo sapiens (Human). Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Gal-3, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein