Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
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Description
MUL1 Polyclonal Antibody. E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Immunogen
n/a
Other Names
C1orf166, GIDE, MAPL, MULAN, RNF218, RP11-401M16.2, E3 SUMO-protein ligase MUL1, E3 ubiquitin ligase, E3 ubiquitin-protein ligase MUL1, growth inhibition and death E3 ligase, mitochondria-anchored protein ligase, mitochondrial E3 ubiquitin ligase 1, mitochondrial ubiquitin ligase activator of NF-kB, mitochondrial