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Description
PAF1, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and CTR9 (MIM 609366) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]). The PAF complex also has a role in histone monoubiquitination (Zhu et al., 2005 [PubMed 16307923]).[supplied by OMIM]. This PAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-467 amino acids from the C-terminal region of human PAF1.
Immunogen
Human PAF1.
Other Names
PAF1; PD2; RNA polymerase II-associated factor 1 homolog; Pancreatic differentiation protein 2; RNA polymerase II associated factor; homolog (S. cerevisiae); F23149_1; FLJ11123; hPAF1