Prostaglandin D Synthase (hematopoietic-type) Inhibitor I
Description
Selectively blocks H-PGDS (IC50s = 0.7 and 32 nM in enzyme and cellular assays, respectively) with little activity against L-PGDS, mPGES, COX-1, COX-2, and 5-LOX; dampens airway hyper-responsiveness in a model of antigen-induced airway response in allergic sheep