Immunocytochemistry: 1:500-1:5000, Immunofluorescence: 1:500-1:5000, Western Blot: 1:500-1:5000
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Description
alpha Synuclein Antibody (14HCLC), ABfinity? Rabbit Oligoclonal. Alpha-Synuclein belongs to the Synuclein family, which includes beta and gamma Synuclein, and is predominantly expressed in neurons, and concentrated at synaptic terminals. Synucleins may be involved in the regulation of dopamine release and transport and the modulation of synaptic vesicle function. Alpha-Synuclein is a small, presynaptic protein that is the major nonamyloid component of the pathological inclusions characteristic of a wide range of neurodegenerative disorders, collectively known as synucleinopathies. Alpha-Synuclein is involved in the formation of SNARE complexes, and most significantly, aggregated alpha-synuclein is one of the major components found in
Immunogen
n/a
Other Names
Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, PARK1, PARK4, PD1, alpha-synuclein, non A-beta component of AD amyloid, synuclein alpha-140