A natural sesquiterpene lactone which inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml); induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription; directly binds the pattern recognition receptor NOD2
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
119325-19-8 120852-67-7 344906-67-8 leishmania apoptosis cancers genes regulations inflammation NF-kB lactones plats feverfew Tanacetum parthenium T. promastigote Leishmania amazonensis L. STAT mediated anti-apoptotic transcriptions inhibits inhibiting inhibition NOD2