fish, porcine, cow, hamster, rabbit, goat, rat, mouse, chicken, human
Isotype
n/a
Format
immunogen affinity purified
Size
100 μg
Concentration
n/a
Applications
ELISA,Western Blotting (WB)
Reviews / Ratings
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Description
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. Though expressed differently in different tissues, GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH is often used as a control in experiments quantifying specific changes in expression levels of other targets. Recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular processes, such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. GAPDH may also play a role in neurodegenerative pathologies such as Huntingtons and Alzheimer-disease. Some physiological factors, such as hypoxia and diabetes, increase GAPDH expression in certain cell types.Goat Anti-GAPDH Polyclonal Antibody is highly purified from goat antiserum by immunoaffinity chromatography.
Immunogen
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from rabbit muscle