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| Antigenic Specificity | Poly (ADP-Ribose) Polymerase 1 (PARP1) (aa 78-91), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Poly[ADP-ribose] polymerase 1(PARP1), also known as ADPRT or PPOL is an enzyme that in humans is encoded by the PARP1 gene. PARP1 gene is mapped to 1q42.12. This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human PARP(78-91aa RWDDQQKVKKTAEA), identical to the related mouse and rat sequences. |
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| Other Names | BEST:LD21673|CG17685|CG17696|CG17718|CG40411|D.PARP|Dm.pARTa|Dmel\\CG40411|LD21673.3prime|PARP|PARP-1|PARP1|dPARP|parp|ADPRT|ADPRT 1|ADPRT1|ARTD1|PPOL|pADPRT-1|Adprt|Parp-1|adprt1|padprt-1|ppol|5830444G22Rik|AI893648|Adprp|Adprt1|C80510|parp-1|sPARP-1 |
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| Gene, Accession # | Gene ID: 25591 |
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| Catalog # | ABIN1673703 |
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| Price | |
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| Order / More Info | Poly (ADP-Ribose) Polymerase 1 (PARP1) (aa 78-91), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 18778284, 22902501 |
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