Western Blotting (WB),Immunohistochemistry (IHC),Immunofluorescence (IF),Flow Cytometry (FACS),ELISA
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Description
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.Synonyms: T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA, CD247
Immunogen
Purified recombinant fragment of human CD247 expressed in E. Coli.