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Description
CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells (1). It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily (2). CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell costimulation and B-cell activation (3,4). It also interacts with TRAFs and is involved in activation of NFκB and SAPK/JNK and induces apoptosis (5-7).Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
Immunogen
Recombinant human CD27 proteinRemarks: Mol. Wt. of Antigen: 120 kDa