Immunohistochemistry: 1:20-1:50, Western Blot: 0.4 μg/mL
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Description
CFHR1 Polyclonal Antibody. This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Immunogen
n/a
Other Names
CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, FHR-1, H factor (complement)-like 1, H factor (complement)-like 2, H-factor-like 1, H36, complement factor H-related 1 pseudogene, complement factor H-related protein 1, h factor-like protein 1