Bridging Integrator 1 (BIN1) (AA 1-439) protein (His tag)
Description
BIN1 is a nucleocytoplasmic adaptor protein, one of which was primarily identified as MYC-interacting protein having the characteristics of a tumor suppressor. BIN1 protein interacts with and inhibits the oncogenic activity of the myc oncoprotein that is a key player in many human cancers. The absence of Bin1 contributes to growth deregulation in cancer cells in carcinoma of the breast, colon, lung, cervix, prostate and liver Synonyms: AMPH2, AMPHL, MGC10367, SH3P9, Amphiphysin II