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Description
Mouse Anti-ZEB2 Recombinant Antibody (923328). This product is a mouse antibody that recognizes ZEB2. The antibody 923328 can be used for immunoassay techniques such as: FC, IHC, CyTOF. The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.
Immunogen
E. coli-derived recombinant human ZEB2/SIP1, Asn363-Lys537.