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Description
Rabbit Anti-IRX3 Recombinant Antibody (BA0099). This product is a rabbit antibody that recognizes IRX3. The antibody BA0099 can be used for immunoassay techniques such as: FC, WB. IRX3 is a member of the Iroquois homeobox gene family and plays a role in an early step of neural development. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos. Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor
Immunogen
Human Iroquois homeobox protein 3 aa 50-150 (Cysteine residue)