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Description
AROS Polyclonal Antibody. AROS, a nucleolar protein with an unknown function, interacts with extraribosomal protein RPS19, playing a role in the signaling pathways that regulate rRNA transcription. The deduced amino acid sequence of AROS, derived from cDNA, defines an isoelectric point of 11.3. No known functional motifs were found in AROS except a short polylysine tract embedded in a putative nucleolar localization signal. At a basal level the protein is expressed ubiquitously with a significantly high level of expression in some tissues. Human AROS gene is mapped to chromosome 22q13.1.