A potent in vitro inhibitor of sn-1 DAGLα (IC50 = 18 nM); blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural substrate of DAGLα, with a Ki value of 0.7 μM; inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6 in membrane preparations (Ki = 0.8 μM)
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
biochemical inhibitor endocannabinoid DAG inhibit human two form diacylglycerol di-acylglycerol lipase DAGL-α DAGL-β DAGLα DAGLβ 2-arachidonoyl glycerol 2-AG 2AG attacking sn-1 position sn1 LEI106 potent in vitro block hydrolysis sn-1-oleoyl-2-arachidonoyl natural substance monoacylglyercol ABHD6 ABHD-6 mouse brain membrane homogenate HEK293T cell preparation HEK-293T HEK293-T HEK-293-T mono-acylglyercol