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| Antigenic Specificity | Complement Component Receptor 1 (CD35) (CR1) |
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| Clone | UJ11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | fluorescein (FITC) conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunofluorescence (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD35 is a receptor for C3b and C4b bound to immune complexes. It is a cofactor for specific proteolytic cleavage of C3b and C4b by plasma serine protease, factor I. Accelerates the decay of both the classical and alternative pathway C3 and C5 convertases on cells to which it is bound (intrinsic activity) and nearby cells (extrinsic activity). The cellular function of CD35 is, on leukocytes and tissue sources, CD35 mediates adherence of C4b/C3b coated particles in preparation for phagocytosis. Phagocytosis most often requires the cooperation of CD35 with complement receptor type 3 (CR3, CD11b/CD18) and the Fcg receptors. Primary function of erythrocyte CD35 is mediating the adherence of targets coated with C4b/C3b and their transport to the fixed phagocyte systems of the spleen and liver. |
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| Immunogen | n/a |
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| Other Names | C3BR|C4BR|CD35|KN|C3DR|CD21|Cr-1|Cr-2|Cr1 |
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| Gene, Accession # | Gene ID: 1378 |
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| Catalog # | ABIN1112119 |
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| Price | |
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| Order / More Info | Complement Component Receptor 1 (CD35) (CR1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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