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Description
CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene. Synonyms: Monoclonal CD4 antibody, Anti-CD4 antibody, Cluster of differentiation 4 antibody, L3T4 antibody, CD4 antigen (p55) antibody, CD4+ Lymphocyte deficiency, CD4_HUMAN antibody, CD4mut antibody, L3T4 antibody, Leu3 antibody, Ly-4 antibody, Lymphocyte antigen CD4 antibody, MGC165891 antibody, p55 antibody, T Cell Antigen T4 antibody.
Immunogen
CD4 antibody was raised in Mouse using a purified recombinant fragment of human CD4 expressed in E. coli as the immunogen.