Recombinant Human Tumor necrosis factor receptor superfamily member 11B protein (TNFRSF11B) (Active)
Description
Purity > 90% as determined by SDS-PAGE. MW: 59.3kDa. Full Length of Mature Protein: 2-296aa. N-terminal GST-tagged. Homo sapiens (Human). Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
33 kDa housekeeping protein; Peroxin-19; Peroxisomal farnesylated protein