Purity > 90% as determined by SDS-PAGE. MW: 25kDa. Full Length: 1-216aa. tag-Free. Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Catalyzes the deamidation of nicotinamide, an early step in the NAD+ salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate.