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Description
CD140b (PDGFRB) Monoclonal Antibody (APB5), eBioscience?. PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of t
Immunogen
n/a
Other Names
PDGF Receptor beta, JTK12, PDGFR, PDGFR1, CD140 antigen-like family member B, PDGF-R-beta, beta-type platelet-derived growth factor receptor